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Dr. Öğr. Üyesi Cemalettin Bekpen

Bahçeşehir Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi

Moleküler Biyoloji ve Genetik Bölümü

MAKALELER

  1. Xie C., Bekpen C., Kunzel S, Keshavarz M, Krebs-Wheaton R, Skrabar N, Ullrich KK, Zhang W., Tautz D.*, (2020) Dedicated transcriptomics combined with power analysis lead to functional understanding of genes with weak phenotypic changes in knockout lines, PLOS Computational Biology November 12, 2020, doi:https://doi.org/10.1371/journal.pcbi.1008354
  2. Xie C., Bekpen C., Künzel S., Keshavarz M., Krebs-Wheaton, R., Skrabar N., Tautz D., (2019), A de novo evolved gene in the house mouse regulates female pregnancy cycles, Elife, . [Epub ahead of print], doi: https://doi.org/10.7554/eLife.44392
  3. *Bekpen C., and Tautz D.*, (2019) Human Core Duplicons; Game Players or Game Changers?ö Briefings in Functional Genomics, doi: https://doi.org/10.1093/bfgp/elz016, Epub, Sept. 16
  4. Bekpen C., Xie C., Tautz D., (2018) Dealing with the adaptive immune system during de novo evolution of genes from intergenic sequences, BMC Evolutionary Biology. 18:121
  5. *Bekpen C., Xie C., Nebel A. and Tautz D.*,(2018) Involvement of SPATA31 copy number variable genes in human lifespan, Aging (Albany NY). 10:674-688
  6. *Bekpen C., Kunzel S., Xie C., Eaaswarkhanth M., Lin YL., Gokcumen O., Akdis CA and Tautz D.*, (2017) Segmental duplications and evolutionary acquisition of UV damage response in the SPATA31 gene family of primates and humans, BMC Genomics, March 6, 18:222
  7. Alkan C., Kavak P., Gökçümen O., Somel M., Uğurlu S., Dal E., Bilge BK, Gungor T., Sahinalp CS., Özören N.*, Bekpen C.*, (2014) Whole genome sequencing of Turkish genomes reveals functional private alleles and impact of genetic interactions with Europe, Asia and Africa, BMC Genomics, Nov 7;15(1):963.
  8. Zaleska A, Eiwegger T, Soyer O, van de Veen W, Rhyner C, Soyka MB, Bekpen C, Demiröz D, Treis A, Söllner S, Palomares O, Kwok WW, Rose H, Senti G, Kündig TM, Ozoren N, Jutel M, Akdis CA, Crameri R, Akdis M.(2014) Immune regulation by intralymphatic immunotherapy with modular allergen translocation MAT vaccine, Allergy, Sep;69(9):1162-70
  9. *Bekpen C., Tastekin I., Siswara P., Akdis CA., *Eichler EE. (2012) Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region, Genome Research, Jun;22(6):1050-8. Epub 2012 Mar 14.
  10. Sin BA., Akdis M., Zumkehr J., Bezzine S., Bekpen C., Lambeau G., Akdis CA., (2011) T Cell and Antibody Responses to Phospholipase A2 from Different Species Show Distinct Cross-Reactivity Patterns, Allergy, 66:12-1513
  11. *Bekpen C., Ramnik X., Eichler EE. (2010) Human IRGM gene “To be or not to be”, Seminars in immunopathology, Dec;32(4):437-44. Epub 2010 Aug 25.
  12. Bekpen C., Marques-B T., Alkan C., Kidd M. J., Siswara P., Antonacci F., Ventura M., Howard JC., Eichler EE. (2009) Death and Resurrection of the Human IRGM gene, PLoS Genet Mar;5(3):e1000403. Epub 2009 Mar 6
  13. Bekpen, C., Hunn, J. P., Rohde, C., Parvanova, I., Guethlein, L., Dunn, D. M., Glowalla, E., Leptin, M., and Howard, J. C. (2005). The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage. Genome Biol 6, R92.
  14. Leonhardt, R. M., Keusekotten, K., Bekpen, C., and Knittler, M. R. (2005). Critical role for the tapasin-docking site of TAP2 in the functional integrity of the MHC class I-peptide-loading complex. J Immunol 175, 5104-5114
  15. *Bekpen C., Baker C., Herbert M., Sahin HB., Johnson M., Celik A., Mullikin J., Eichler EE., (2017) Functional characterization of morpheus gene family, bioRxiv: doi: https://doi.org/10.1101/116087, March 12

KONFERANS BİLDİRİLERİ

  1. Bekpen C, and Tautz D., (6-9 September 2018), Involvement of SPATA31 copy number variable genes in human lifespan, Jena Aging Meeting, Jena/Germany,
  2. Bekpen C., Xie C., Nebel A. and Tautz D. (1-2 December 2017) Involvement of SPATA31 copy number variable genes in human lifespan, Annual Meeting of the German Foundation for Aging Research (DGfA), Cologne/Germany,
  3. Bekpen C., Tautz D. Birth of a new gene: the problem of self-tolerance versus autoimmune reaction SMBE 2017 / USA,
  4. Bekpen C., Xie C., Nebel A. and Tautz D. (11-16 June 2017) Copy number variation of SPATA31A antagonistically correlates with germline and somatic mutation rates and shorter life span in humans, Gordon Research Conference, Molecular Mechanisms of Evolution, Boston/USA,
  5. Bekpen C., Tautz D. (14-17 Sep. 2016) Birth of a new gene: the problem of self-tolerance versus autoimmune reaction, 109th Annual Meeting of the German Zoological Society 2016 Kiel/ Germany,
  6. Bekpen C., Tautz D. Birth of a new gene: the problem of self-tolerance versus autoimmune reaction SMBE 2016 / Australia,
  7. Bekpen C., Tautz D. Evolutionary and functional characterization of SPATA31 gene family SMBE 2015 / Austria,
  8. Bekpen C., Tautz D. Evolutionary and functional characterization of Human Core Duplicons SMBE 2014 / Puerto Rico,
  9. Giannuzzi G., Bekpen C., Siswara P., Ventura M., Eichler EE. (18-21 May. 2010) Evolution of LRRC37 primate gene family from a functional perspective, 14th Human Genome Meeting 2010 Montpellier/ France,
  10. Bekpen C. (15-17 Apr. 2009) Comparative genomics analysis and dynamic structure of segmentally duplicated gene families,International Symposium on Health Informatics and Bioinformatics, (HIBIT) Ankara / Turkey,
  11. Bekpen et al., (2005) (10-12 Nov. 2005) The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell-autonomous resistance mechanism in the human lineage, International Symposium on Health Informatics and Bioinformatics, (HIBIT) Antalya / Turkey,
  12. Bekpen C., J. Hunn, I. Parvanova, E. Glowalla, L. Guethlein, J. Howard, (26-30 May. 2004) Systematics and evolution of the p47 resistance GTPases; Gain and loss of immune function, ENII-EMBO Workshop on Mechanisms of Immunity, Ile des Embiez / France,
  13. Bekpen C., J. Hunn, S. Martens, I. Parvanova, S. Weisshaar, and J. Howard, (24-27 Sept. 2003) Mediators of cell-autonomous immunity: the p47 GTPases, 34th Annual Meeting of the German Society of Immunology, Berlin / Germany, Immunobiology, Volume 208, Number 1-3, 2003,

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